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Vaccination and side effects
Vaccine Side Effects
A vaccine side effect can be defined as an adverse reaction to a vaccine.
Vaccines will have some side effects such as pain, redness, swelling, or a small lump at the site of injection.
These local side effects usually resolve in a few days, although lumps may take weeks or longer to resolve.
The vaccines may also have some general side effects like fever, headache, muscle aches and pains, or a rash - these side effects may be caused by the vaccine or may be symptoms of a coincidental illness (e.g. viral infection).
Rarely, the vaccine will cause a severe allergic reaction, which is called as anaphylaxis, that begins minutes after vaccination. This includes symptoms such as severe anxiety, hives (itchy skin rash), swelling of the lips and face, difficulty breathing, or collapse. The treatment for anaphylaxis is the immediate injection of adrenaline, which stops the allergic reaction.
If a vaccine side effect occurs following one of a series of vaccinations, then, unless the side effect was severe, the series of vaccinations should be completed. If you are concerned about completing a series of vaccinations after a vaccine side effect, then consult your immunisation provider.
To reduce pain from vaccinations
Give paracetamol – do not exceed the recommended maximum dosage on the label. Doses of paracetamol should not usually be given less than 4 hours apart.
Place a cold, wet cloth over the injection site for pain, redness, or swelling. Note that some infants may not move a limb while the injection site is painful – this will resolve as the pain disappears.
To reduce fever from vaccinations :
Give extra fluids (e.g. more breast feeds or water) to prevent dehydration.
Cool the child slowly by removing extra clothing or fanning. Bathing in cool water is not recommended because it may cause shivering, which can increase the core body temperature.
Give paracetamol.
The following table summarises the side effects of the scheduled vaccines. Note that the side effects may vary with the age of the person.
| Vaccine |
Side Effects |
Full name: Diphtheria-Tetanus- Pertussis-Polio-
Hepatitis B-Haemophilus influenzae type b
Abbreviation: DTPa-IPV-HepB-Hib
|
Fever - about 1 child in 4
Soreness, redness, lump at the injection site - about 1 child in 4
Vomiting - about 1 child in 50
Prolonged crying - about 1 child in 1,000
Febrile seizure - about 1 child in 14,000
High fever (over 400C) - about 1 child in 16,000
Allergic reaction - less than 1 child in a million |
Full name: Diphtheria-Tetanus- Pertussis-Polio-Hepatitis B
Abbreviation: DTPa-IPV-HepB |
Same as above |
Full name: Diphtheria-Tetanus- Pertussis-Polio
Abbreviation: DTPa-IPV |
Fever, soreness, redness, lump at the injection site - about 1 child in 10
Headache, vomiting - about 1 child in 20 |
Full name: Adult Diphtheria-Tetanus- Pertussis
Abbreviation: dTpa |
Headache, fatigue – about 1 child in 2
Fever, soreness, lump at the injection site – about 1 child in 10 |
Full name: 7 valent Pneumococcal Conjugate Vaccine
Abbreviation: 7vPCV |
Fever, soreness, redness, lump
at the injection site - about 1 child in 4 |
Full name: Haemophilus influenzae
type b |
Abbreviation: Hib
Irritability – about 1 child in 2
Soreness, redness, lump at the injection site - about 1 child in 4
Fever - about 1 child in 7
Vomiting, prolonged crying - about 1 child in 50 |
| Full name: Meningococcal C Conjugate Vaccine |
Abbreviation: MCCV
Headache – about 1 older child or adult in 4
Soreness, redness, lump at the injection site - about 1 child in 10
Fever - about 1 child in 10 |
Full name: Measles-Mumps-Rubella
Abbreviation: MMR |
Fever 5-12 days after vaccination - about 1 child in 6
Discomfort at the injection site - about 1 child in 10
Non-infectious rash 5-12 days after vaccination - about 1 child in 20
Pain and stiffness in the joints - about 1 older child or adult in 4
Febrile seizure - about 1 child in 3,000
Thrombocytopaenia (low platelet count) - about 1 child in 30,000
Allergic reaction - less than 1 child in a million
Encephalitis (inflammation of the brain) - about 1 child in 3 million |
Full name: Hepatitis A
Abbreviation: HepA |
Fever - about 1 child in 10
Soreness, redness, lump at the injection site - about 1 child in 20
Rash - about 1 child in 100 |
Full name: 23 valent Pneumococcal Polysaccharide Vaccine
Abbreviation: 23vPPV |
Soreness, redness, lump at the injection site - about 1 child in 4
Fever, muscle pain - less than 1 child in 100 |
Full name: Varicella (chickenpox)
Abbreviation: VZV |
Soreness, redness, lump at the injection site - about 1 child in 5
Fever - about 1 child in 10
Rash - about 1 child in 20
Febrile seizure – about 1 child in 1,000 |
Full name: Hepatitis B
Abbreviation: HepB |
Soreness at the injection site – about 1 child in 10
Fever, dizziness, tiredness, sweating, muscle pain, insomnia, earache - less than 1 child in 100
Nausea, diarrhoea - less than 1 child in 200 |
Full name: Adult Diphtheria-Tetanus
Abbreviation: dT |
Soreness, redness, lump at the injection site – about 1 person in 5 Brachial neuritis (nerve inflammation) – about 1 person in 100,000 |
| Full name: Influenza |
Soreness, redness, lump at the injection site – about 1 person in 10 Guillain-Barre Syndrome (ascending paralysis) - about 1 person in 1 million |